DETAILS, FICTION AND NAD+ AND ITS EFFECT ON DNA REPAIR

Subsequent, we addressed cells with various concentrations of NAD+. When additional for 24 h at 80 µM in HeLa and four hundred µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Prolonged Knowledge Fig. 1k,l). Furthermore, 16 µM of NAD+ was adequate to cut back fork pace by ~40% in HeLa cells with out affecting the who